COVID-19 infection in known epileptic and non-epileptic children: what is the place of chloroquine sulfate? (a case report).
Pan Afr Med J
; 37: 177, 2020.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1031188
ABSTRACT
The coronavirus 19 (COVID-19) disease, which was declared in China in December 2019, very early on became a pandemic, claiming more than 28 million victims worldwide to date. Its impact on the central nervous system is still poorly understood. The objective of this work is to assess the involvement of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in the aggravation of seizures in children known to have epilepsy and in the epileptogenesis of children hitherto seizure-free. Prior to conducting this work, we had obtained informed consent from patients and parents. We report the cases of three (3) patients, one known epileptic and the other two apparently healthy, who presented a febrile seizure in a context of COVID-19 infection. The aggravation of the epileptic seizure was indicative of a SARS-CoV-2 infection in the first patient, while the seizure occurred after induction of chloroquine sulfate treatment in the 2 other patients. Although our current concern is to limit the spread of the disease to COVID-19, it is crucial to address its possible complications. Notably, the worsening of seizures in children with epilepsy and the occurrence of first seizures in children without epilepsy following drug treatment. Equipping our COVID-19 patient management facilities with electroencephalogram (EEG) equipment could facilitate continuous electroencephalographic monitoring of children for proper management.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Cloroquina
/
Convulsiones Febriles
/
Epilepsia
/
COVID-19
Tipo de estudio:
Reporte de caso
/
Estudios diagnósticos
Tópicos:
Covid persistente
Límite:
Adolescente
/
Niño
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Pan Afr Med J
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Pamj.2020.37.177.26066
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