Is COVID Evolution Due to Occurrence of Pulmonary Vascular Thrombosis?
J Thorac Imaging
; 35(6): 344-345, 2020 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1219915
ABSTRACT
In this hypothesis paper, we suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce intravascular pulmonary thrombosis, which may result in the rapid worsening of clinical conditions and, eventually, exitus. Previously published papers have demonstrated that increased levels of D-dimer at hospital admission correlate with a more severe disease (0.5 mg/L) or occurrence of death (1 mg/L). The potential prothrombotic action of the SARS-CoV-2 is supported by the topographical involvement of the lung regions with a predilection for the lower lobe with peripheral involvement. If this hypothesis is demonstrated, this could suggest the benefit of using antithrombotic/coagulation regimens for SARS-CoV-2 and, at the same time, the urgency to identify drugs that could alter the inflammatory storm, thus protecting the vessel wall.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Trombosis
/
COVID-19
Tipo de estudio:
Estudio pronóstico
Tópicos:
Covid persistente
Límite:
Humanos
Idioma:
Inglés
Revista:
J Thorac Imaging
Asunto de la revista:
Diagnóstico por Imagen
Año:
2020
Tipo del documento:
Artículo
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