Immune system and COVID-19 by sex differences and age.
Womens Health (Lond)
; 17: 17455065211022262, 2021.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1259152
ABSTRACT
In COVID-19 disease, are reported gender differences in relation to severity and death. The aim of this review is to highlight gender differences in the immune response to COVID-19. The included studies were identified using PubMed, until 30 October 2020. The search included the following keywords SARS-CoV-2, COVID-19, gender, age, sex, and immune system. Literature described that females compared to males have greater inflammatory, antiviral, and humoral immune responses. In female, estrogen is a potential ally to alleviate SARS-COV-2 disease. In male, testosterone reduces vaccination response and depresses the cytokine response. In the older patients, and in particular, in female older patients, it has been reported a progressive functional decline in the immune systems. Differences by gender were reported in infection diseases, including SARS-CoV-2. These data should be confirmed by the other epidemiological studies.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Factores Sexuales
/
COVID-19
/
Sistema Inmunológico
/
Inmunidad
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Revisiones
Tópicos:
Vacunas
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Womens Health (Lond)
Asunto de la revista:
Salud de la Mujer
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
17455065211022262
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