Revolutionizing polymer-based nanoparticle-linked vaccines for targeting respiratory viruses: A perspective.
Life Sci
; 280: 119744, 2021 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1281492
ABSTRACT
Viral respiratory tract infections have significantly impacted global health as well as socio-economic growth. Respiratory viruses such as the influenza virus, respiratory syncytial virus (RSV), and the recent SARS-CoV-2 infection (COVID-19) typically infect the upper respiratory tract by entry through the respiratory mucosa before reaching the lower respiratory tract, resulting in respiratory disease. Generally, vaccination is the primary method in preventing virus pathogenicity and it has been shown to remarkably reduce the burden of various infectious diseases. Nevertheless, the efficacy of conventional vaccines may be hindered by certain limitations, prompting the need to develop novel vaccine delivery vehicles to immunize against various strains of respiratory viruses and to mitigate the risk of a pandemic. In this review, we provide an insight into how polymer-based nanoparticles can be integrated with the development of vaccines to effectively enhance immune responses for combating viral respiratory tract infections.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Polímeros
/
Infecciones del Sistema Respiratorio
/
Vacunas Virales
/
Vacunación
/
Nanopartículas
Tipo de estudio:
Estudio pronóstico
Tópicos:
Vacunas
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Life Sci
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
J.lfs.2021.119744
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