Long COVID in a prospective cohort of home-isolated patients.
Nat Med
; 27(9): 1607-1613, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1290003
ABSTRACT
Long-term complications after coronavirus disease 2019 (COVID-19) are common in hospitalized patients, but the spectrum of symptoms in milder cases needs further investigation. We conducted a long-term follow-up in a prospective cohort study of 312 patients-247 home-isolated and 65 hospitalized-comprising 82% of total cases in Bergen during the first pandemic wave in Norway. At 6 months, 61% (189/312) of all patients had persistent symptoms, which were independently associated with severity of initial illness, increased convalescent antibody titers and pre-existing chronic lung disease. We found that 52% (32/61) of home-isolated young adults, aged 16-30 years, had symptoms at 6 months, including loss of taste and/or smell (28%, 17/61), fatigue (21%, 13/61), dyspnea (13%, 8/61), impaired concentration (13%, 8/61) and memory problems (11%, 7/61). Our findings that young, home-isolated adults with mild COVID-19 are at risk of long-lasting dyspnea and cognitive symptoms highlight the importance of infection control measures, such as vaccination.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Disnea
/
Fatiga
/
Disfunción Cognitiva
/
COVID-19
/
Anticuerpos Antivirales
Tipo de estudio:
Estudio de cohorte
/
Estudio observacional
/
Estudio pronóstico
Tópicos:
Covid persistente
/
Vacunas
Límite:
Adolescente
/
Adulto
/
Niño
/
Child, preschool
/
Femenino
/
Humanos
/
Lactante
/
Masculino
/
Middle aged
/
Young_adult
País/Región como asunto:
Europa
Idioma:
Inglés
Revista:
Nat Med
Asunto de la revista:
Biologia Molecular
/
Medicina
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
S41591-021-01433-3
Similares
MEDLINE
...
LILACS
LIS