Urticarial vasculitis: A potential signpost for multisystem inflammatory syndrome in children.
J Cutan Pathol
; 49(2): 163-166, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1409914
ABSTRACT
Multisystem inflammatory syndrome in children (MIS-C) is a rare and serious complication of Sars-Cov-2 infection. Dermatologic manifestations are present in the majority of patients. Skin lesions found in children with MIS-C are classified into four categories morbilliform, reticulated, scarlatiniform, and urticarial lesions. Clinicopathologic characterization within these categories is limited. Thus, we present a clear example of an urticarial lesion in the context of MIS-C with well-documented clinicopathologic phenomena. A previously healthy 16-year-old female presented with 3 weeks of an itchy, burning rash initially presenting on her right forearm (and lasting greater than 24 hours without migration) before spreading diffusely. She also reported fever, cough, myalgias, nausea, and vomiting of 4 weeks' duration. Physical examination revealed an edematous, maculopapular, nonblanching, erythematous rash covering the patient's upper extremities, abdomen, back, anterior thighs, and face. The patient tested positive for COVID-19. A low-grade leukocytoclastic vasculitis was noted along with intraluminal fibrin and rare microthrombi in vessels of the mid to deep dermis. The patient was diagnosed with MIS-C and urticarial vasculitis. She was treated with steroids and naproxen for subsequent MIS-C flares. Dapsone treatment was started for the urticarial vasculitis.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Urticaria
/
Vasculitis Leucocitoclástica Cutánea
/
Síndrome de Respuesta Inflamatoria Sistémica
/
COVID-19
Tipo de estudio:
Reporte de caso
Tópicos:
Covid persistente
Límite:
Adolescente
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
J Cutan Pathol
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
Cup.14134
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