Modification of immunosuppressive agents in a kidney transplant recipient with COVID-19 and acute kidney injury.
J Infect Dev Ctries
; 15(9): 1273-1276, 2021 09 30.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1478140
ABSTRACT
INTRODUCTION:
An outbreak of coronavirus disease-19 (COVID-19) has occurred in different parts of the world. Although a large piece of information regarding the epidemiology, clinical features, and management of COVID-19 has been reported in the general population, there is very limited data regarding organ transplant recipients, particularly regarding the management of maintenance immunosuppressive agents during infection.METHODOLOGY:
We described a case of kidney transplant recipient from Thailand who had COVID-19 pneumonia and severe acute kidney injury.RESULTS:
The patient's serum creatinine peaked at 7.0 mg/dL on day 15 of illness and returned to baseline value of 2.0 mg/dL on day 26 of illness. We have shown how we modified tacrolimus, mycophenolate, and steroids in the patient who had received favipiravir and lopinavir/ritonavir for COVID-19 pneumonia.CONCLUSIONS:
In this case, successful modification of this immunosuppressive regimen was accomplished to reduce drug interaction complications, aiming to avoid calcineurin inhibitor nephrotoxicity while maintaining appropriate levels of immunosuppression to prevent organ rejection and to promote the patient's recovery from infection.Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Lesión Renal Aguda
/
Tratamiento Farmacológico de COVID-19
/
Inmunosupresores
Tipo de estudio:
Reporte de caso
/
Estudio pronóstico
Límite:
Adulto
/
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
J Infect Dev Ctries
Asunto de la revista:
Enfermedades Transmisibles
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
Jidc.13176
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