Specific Susceptibility to COVID-19 in Adults with Down Syndrome.
Neuromolecular Med
; 23(4): 561-571, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1525619
ABSTRACT
The current SARS-CoV-2 outbreak, which causes COVID-19, is particularly devastating for individuals with chronic medical conditions, in particular those with Down Syndrome (DS) who often exhibit a higher prevalence of respiratory tract infections, immune dysregulation and potential complications. The incidence of Alzheimer's disease (AD) is much higher in DS than in the general population, possibly increasing further the risk of COVID-19 infection and its complications. Here we provide a biological overview with regard to specific susceptibility of individuals with DS to SARS-CoV-2 infection as well as data from a recent survey on the prevalence of COVID-19 among them. We see an urgent need to protect people with DS, especially those with AD, from COVID-19 and future pandemics and focus on developing protective measures, which also include interventions by health systems worldwide for reducing the negative social effects of long-term isolation and increased periods of hospitalization.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Down
/
Susceptibilidad a Enfermedades
/
COVID-19
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Tópicos:
Covid persistente
/
Vacunas
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Neuromolecular Med
Asunto de la revista:
Biologia Molecular
/
Neurología
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
S12017-021-08651-5
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