aPDT for oral decontamination of hospitalized patients with COVID 19.
Photodiagnosis Photodyn Ther
; 38: 102762, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1683501
ABSTRACT
Emerging variants of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) may have an impact on the virus's transmissibility and pathogenicity and an increased risk of reinfection. Antimicrobial photodynamic therapy (aPDT) is a promising technique to decontaminate the oral cavity to minimize and inactivate microorganisms' load. This article reports through a case series, a proposal for efficient oral decontamination for hospitalized patients with COVID 19 using aPDT. Samples of oral tissues were obtained after aPDT and analyzed using two methods of RT-qPCR to elucidate qualitative and quantitative viral profiles of SARS-CoV-2 RNA in the oral cavity. There was a reduction of viral load in the oral cavity immediately or one hour after the use of aPDT. This method could be a good option to decontaminate the oral cavity to minimize and inactivate microorganism load.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Fotoquimioterapia
/
COVID-19
Tipo de estudio:
Estudio pronóstico
/
Investigación cualitativa
Tópicos:
Variantes
Límite:
Humanos
Idioma:
Inglés
Revista:
Photodiagnosis Photodyn Ther
Asunto de la revista:
Diagnóstico por Imagen
/
Terapeutica
Año:
2022
Tipo del documento:
Artículo
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