Myocarditis following mRNA COVID-19 vaccination: call for endomyocardial biopsy.
ESC Heart Fail
; 9(3): 1996-2002, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1704932
ABSTRACT
Acute myocarditis following mRNA COVID-19 vaccination was reported by the European Medicine Agency safety committee as a rare adverse event. We present a case series of three young male patients with suspected acute myocarditis following BNT162b2 mRNA COVID-19 vaccination including results of endomyocardial biopsies (EMB). Additionally, we analysed EMB of another 21 patients with clinically suspected acute myocarditis following vaccination to determine the pathohistological pattern. Overall, EMB revealed acute lymphocytic myocarditis in 5 (20.8%), chronic lymphocytic myocarditis in 6 (25%), cardiac sarcoidosis in 1 (4.2%), healed myocarditis in 6 (25%), and other diagnoses with cardiac damage of unclear aetiology in 6 (25%) cases. Our findings support the necessity of EMB in patients with suspected acute myocarditis following mRNA COVID-19 vaccination presenting with reduced EF to establish a correct and definite diagnosis. Concerns of these rare severe adverse events after COVID-19 immunization should not undermine its value for the global community.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
COVID-19
/
Miocarditis
Tipo de estudio:
Reporte de caso
/
Estudios diagnósticos
/
Estudio de etiologia
/
Estudio observacional
/
Estudio pronóstico
Tópicos:
Vacunas
Límite:
Humanos
/
Masculino
Idioma:
Inglés
Revista:
ESC Heart Fail
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
Ehf2.13791
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