Current status of potential therapeutic candidates for the COVID-19 crisis.
Brain Behav Immun
; 87: 59-73, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1719339
ABSTRACT
As of April 15, 2020, the ongoing coronavirus disease 2019 (COVID-2019) pandemic has swept through 213 countries and infected more than 1,870,000 individuals, posing an unprecedented threat to international health and the economy. There is currently no specific treatment available for patients with COVID-19 infection. The lessons learned from past management of respiratory viral infections have provided insights into treating COVID-19. Numerous potential therapies, including supportive intervention, immunomodulatory agents, antiviral therapy, and convalescent plasma transfusion, have been tentatively applied in clinical settings. A number of these therapies have provided substantially curative benefits in treating patients with COVID-19 infection. Furthermore, intensive research and clinical trials are underway to assess the efficacy of existing drugs and identify potential therapeutic targets to develop new drugs for treating COVID-19. Herein, we summarize the current potential therapeutic approaches for diseases related to COVID-19 infection and introduce their mechanisms of action, safety, and effectiveness.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Neumonía Viral
/
Infecciones por Coronavirus
Tipo de estudio:
Estudio pronóstico
Tópicos:
Medicina tradicional
/
Vacunas
Idioma:
Inglés
Revista:
Brain Behav Immun
Asunto de la revista:
Alergia e Inmunología
/
Cérebro
/
Psicofisiología
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
J.bbi.2020.04.046
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