Histopathology of persistent long COVID toe: A case report.
J Cutan Pathol
; 49(9): 791-794, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1774773
ABSTRACT
During the 2020 coronavirus (SARS-CoV-2) pandemic, several cutaneous lesions were identified, including pseudo-chilblain, vesicular, urticarial, maculopapular, and livedo/necrosis. A 59-year-old obese man with probable COVID-19 developed painful cyanosis with histopathologic capillary thrombosis of toes, and the cyanosis persisted for nearly 22 months. Shortly after initial exposure to family members with documented SARS-CoV-2, he developed upper respiratory symptoms, yet his anti-SARS-CoV-2 antibody and nasal swab RT-PCR tests were repeatedly negative. Two family members were hospitalized and one of them succumbed with documented SARS-CoV-2 pneumonia within 10 days of exposure. Biopsy specimen of the distal toe 16 weeks after initial exposure showed papillary dermal capillary thrombosis with endothelial swelling, telangiectasia, and peri-eccrine lymphocytic infiltrates resembling pernio. Overall, this is the first case of biopsy specimen of "long COVID toe" following presumed SARS-CoV-2 exposure, with a demonstration of thrombotic vasculopathy, toe cyanosis, and pernio-like pathology.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Trombosis
/
Dedos del Pie
/
Cianosis
/
COVID-19
Tipo de estudio:
Reporte de caso
Tópicos:
Covid persistente
Límite:
Humanos
/
Masculino
/
Middle aged
Idioma:
Inglés
Revista:
J Cutan Pathol
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
Cup.14240
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