Airway administration of bisphosphate and dexamethasone inhibits SARS-CoV-2 variant infection by targeting alveolar macrophages.

Wang, Zhenfeng; Zhou, Yabo; Bao, Linlin; Li, Dan; Lv, Jiadi; Wang, Dianheng; Li, Shunshun; Liu, Jiangning; Qin, Chuan; Tong, Wei-Min; Huang, Bo

Wang, Zhenfeng; Zhou, Yabo; Bao, Linlin; Li, Dan; Lv, Jiadi; Wang, Dianheng; Li, Shunshun; Liu, Jiangning; Qin, Chuan; Tong, Wei-Min; Huang, Bo.

Wang Z; Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, 100005, Beijing, China.
Zhou Y; Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, 100005, Beijing, China.
Bao L; NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Institute of Laboratory Animal Science, CAMS and Comparative Medicine Center, Peking Union Medical College, Beijing, China.
Li D; NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Institute of Laboratory Animal Science, CAMS and Comparative Medicine Center, Peking Union Medical College, Beijing, China.
Lv J; Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, 100005, Beijing, China.
Wang D; Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, 100005, Beijing, China.
Li S; Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, 100005, Beijing, China.
Liu J; NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Institute of Laboratory Animal Science, CAMS and Comparative Medicine Center, Peking Union Medical College, Beijing, China.
Qin C; NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Institute of Laboratory Animal Science, CAMS and Comparative Medicine Center, Peking Union Medical College, Beijing, China. qinchuan@pumc.edu.cn.
Tong WM; Department of Pathology, Institute of Basic Medical Sciences, CAMS and Peking Union Medical College, Beijing, China. Weiminfr@hotmail.com.
Huang B; Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, 100005, Beijing, China. tjhuangbo@hotmail.com.

Signal Transduct Target Ther ; 7(1): 116, 2022 04 06.

Artículo en Inglés | MEDLINE | ID: covidwho-1778595

Asunto(s)

Tratamiento Farmacológico de COVID-19; Macrófagos Alveolares; Dexametasona/farmacología; Humanos; SARS-CoV-2

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Macrófagos Alveolares / Tratamiento Farmacológico de COVID-19 Tópicos: Variantes Límite: Humanos Idioma: Inglés Revista: Signal Transduct Target Ther Año: 2022 Tipo del documento: Artículo País de afiliación: S41392-022-00977-1

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