Mechanism of COVID-19 Causing ARDS: Exploring the Possibility of Preventing and Treating SARS-CoV-2.
Front Cell Infect Microbiol
; 12: 931061, 2022.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1924082
ABSTRACT
Novel coronavirus pneumonia (COVID-19) is spreading worldwide, causing great harm and stress to humans. Since patients with novel coronavirus (SARS-CoV-2) have a high probability of developing acute respiratory distress syndrome (ARDS) in severe cases, the pathways through which SARS-CoV-2 causes lung injury have become a major concern in the scientific field. In this paper, we investigate the relationship between SARS-CoV-2 and lung injury and explore the possible mechanisms of COVID-19 in ARDS from the perspectives of angiotensin-converting enzyme 2 protein, cytokine storm, activation of the immune response, triggering of Fas/FasL signaling pathway to promote apoptosis, JAK/STAT pathway, NF-κB pathway, type I interferon, vitamin D, and explore the possibility of prevention and treatment of COVID-19. To explore the possibility of SARS-CoV-2, and to provide new ideas to stop the development of ARDS in COVID-19 patients.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Dificultad Respiratoria
/
Lesión Pulmonar
/
COVID-19
Tipo de estudio:
Estudio observacional
Tópicos:
Covid persistente
Límite:
Humanos
Idioma:
Inglés
Revista:
Front Cell Infect Microbiol
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
Fcimb.2022.931061
Similares
MEDLINE
...
LILACS
LIS