Flavivirus-host interactions: an expanding network of proviral and antiviral factors.
Curr Opin Virol
; 52: 71-77, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1936243
ABSTRACT
Flaviviruses are zoonotic pathogens transmitted by the bite of infected mosquitos and ticks and represent a constant burden to human health. Here we review recent literature aimed at uncovering how flaviviruses interact with the cells that they infect. A better understanding of these interactions may ultimately lead to novel therapeutic targets. We highlight several studies that employed low-biased methods to discover new protein-protein, protein-RNA, and genetic interactions, and spotlight recent work characterizing the host protein, TMEM41B, which has been shown to be critical for infection by diverse flaviviruses and coronaviruses.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Infecciones por Flavivirus
/
Flavivirus
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Curr Opin Virol
Año:
2022
Tipo del documento:
Artículo
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