Comparison of Vitamin D, Interleukin-6, and Interleukin-8 Levels in Covid Positive patients with or without Cytokines Storm
Pakistan Journal of Medical and Health Sciences
; 16(6):192-193, 2022.
Artículo
en Inglés
| EMBASE | ID: covidwho-1939786
ABSTRACT
Background:
Currently world is within the clutches of the coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, COVID-19 virus has evolved to human-to-human spread . COVID-19 infection can cause fever, fatigue, dry cough, severe pneumonia, respiratory distress syndrome and in some instances death. Release of cytokine is the main process by which COVID-19 affects human system. High level of chemokines and pro-inflammatory cytokines has been observed among the patients with COVID-19.Methodology:
100 COVID-19 positive patients with cytokine storm and100 COVID-19 positive patients without cytokine storm with 18+ age and both gender were included after their formal consent. Interleukin-6, interleukin-8 and Vitamin-D were determined by their respective ELISA kits. SPSS software was applied for statistical analysis.Results:
the results of current study showed the raised levels of interleukin-6 and interleukin 8 in case group as compared to controls. Levels of Vit D were compromised in case of Covid patients with cytokine storm than controls respectively.Conclusion:
it was concluded that increased oxidative stress and lacking anti-oxidants may add to the development and advancement of cytokine storm in corona virus positive patients.
ELISA kit; interleukin 1; interleukin 6; interleukin 8; malonaldehyde; superoxide dismutase; transforming growth factor beta; vitamin D; adult; article; controlled study; coronavirus disease 2019; cytokine release; cytokine storm; enzyme linked immunosorbent assay; female; human; major clinical study; male; oxidative stress; protein blood level; teaching hospital
Texto completo:
Disponible
Colección:
Bases de datos de organismos internacionales
Base de datos:
EMBASE
Idioma:
Inglés
Revista:
Pakistan Journal of Medical and Health Sciences
Año:
2022
Tipo del documento:
Artículo
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