Incidence, hospitalization, and mortality in children aged 5 years and younger with respiratory syncytial virus-related diseases: A systematic review and meta-analysis.
Influenza Other Respir Viruses
; 17(5): e13145, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: covidwho-20235048
ABSTRACT
Objectives:
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in young children. We aimed to analyze the factors affecting the estimation of RSV-related disease burden, and to provide evidence to help establish a surveillance system.Methods:
We searched the English- and Chinese-language databases for articles published between January 1, 2010 and June 2, 2022. The quality of the included articles was assessed using the Agency for Healthcare Research and Quality scale. Random-effects models were used for data synthesis and subgroup analyses. This review was registered in the Prospective Register of Systematic Reviews (PROSPERO CRD42022372972).Results:
We included 44 studies (149,321,171 participants), all of which were of medium or high quality. The pooled RSV-related disease incidence, hospitalization rate, in-hospital mortality, and overall mortality rates in children aged 5 years and younger were 9.0 per 100 children per year (95% confidence interval [CI] 7.0-11.0), 1.7 per 100 children per year (95% CI 1.3-2.1), 0.5 per 100 children per year (95% CI 0.4-0.5), and 0.05 per 100 children per year (95% CI 0.04-0.06), respectively. Age, economics, surveillance types, case definition, and data source were all recognized as influencing factors.Conclusions:
A standardized and unified RSV surveillance system is required. Case definition and surveillance types should be fully considered for surveillance of different age groups.Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Infecciones del Sistema Respiratorio
/
Virus Sincitial Respiratorio Humano
/
Infecciones por Virus Sincitial Respiratorio
Tipo de estudio:
Estudio experimental
/
Estudio observacional
/
Estudio pronóstico
/
Ensayo controlado aleatorizado
/
Revisiones
/
Revisión sistemática/Meta análisis
Límite:
Niño
/
Child, preschool
/
Humanos
País/Región como asunto:
America del Norte
Idioma:
Inglés
Revista:
Influenza Other Respir Viruses
Asunto de la revista:
Virología
Año:
2023
Tipo del documento:
Artículo
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