Immunogenetic landscape of COVID-19 infections related neurological complications
COVID-19 in Alzheimer's Disease and Dementia
; : 133-146, 2023.
Artículo
en Inglés
| Scopus | ID: covidwho-20237680
ABSTRACT
The human leukocyte antigen (HLA) is a critical component of antigen presentation and plays crucial role in conferring differential susceptibility and severity of diseases caused by viruses such as COVID-19. The immunogenetic profile of populations, BCG vaccination status, and a host of lifestyle factors might contribute to the observed variations in mortality rates due to COVID-19. These genetic, epigenetic, and environmental factors could widely influence infection dynamics and immune responses against COVID-19. The aim of this review is to provide an update on HLA association with SARS-CoV-2 infection in global populations and to highlight the possible neurological involvements. We also set out to explore the HLA immunogenetic markers related to COVID‐19 infections that can be used in screening high‐risk individuals for personalized therapies and in community-based vaccine development. © 2023 Elsevier Inc. All rights reserved.
Texto completo:
Disponible
Colección:
Bases de datos de organismos internacionales
Base de datos:
Scopus
Tipo de estudio:
Estudio pronóstico
Tópicos:
Vacunas
Idioma:
Inglés
Revista:
COVID-19 in Alzheimer's Disease and Dementia
Año:
2023
Tipo del documento:
Artículo
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