Overview of interleukin-6 levels in COVID-19 (coronavirus disease 2019) patients at Dr. M. Djamil General Hospital, Padang, Indonesia
Bioscientia Medicina
; 7(3):3173-3177, 2023.
Artículo
en Inglés
| GIM | ID: covidwho-20241678
ABSTRACT
Background:
COVID-19 infection can cause an exaggerated immune response. This immune response is associated with an increase in proinflammatory cytokines, especially interleukin-6 (IL-6). High IL-6 levels are found in the acute stage of COVID-19, and IL-6 can induce an excessive humoral inflammatory response. This study aimed to provide an overview of IL-6 levels in coronavirus disease 2019 (COVID-19) patients at Dr. M. Djamil General Hospital, Padang, Indonesia.Methods:
Descriptive observational study of 102 research subjects. Observations on sociodemographic, clinical, and laboratory data were carried out in this study. Univariate analysis was carried out using SPSS version 25.Results:
Patients with symptom onset <7 days had higher IL-6 levels than those with an onset of more than 7 days. Patients with critical degrees have the highest IL-6 levels compared to moderate and severe degrees. Patients with more than 1 comorbid had higher IL-6 levels than patients who had no comorbid or only had 1 comorbid. Patients with <21 days of treatment had higher IL-6 levels than patients with more than 21 days of treatment.Conclusion:
COVID-19 patients at Dr. M. Djamil General Hospital, Padang, Indonesia, with an onset of less than 7 days, a critical degree, and more than 1 comorbidity have higher IL-6 levels.
human diseases; coronavirus disease 2019; viral diseases; interleukin 6; immune response; cytokines; inflammation; humoral immunity; observational studies; symptoms; man; Severe acute respiratory syndrome coronavirus 2; Indonesia; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; APEC countries; ASEAN Countries; high Human Development Index countries; lower-middle income countries; South East Asia; Asia; SARS-CoV-2; viral infections; immunity reactions; immunological reactions
Texto completo:
Disponible
Colección:
Bases de datos de organismos internacionales
Base de datos:
GIM
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Idioma:
Inglés
Revista:
Bioscientia Medicina
Año:
2023
Tipo del documento:
Artículo
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