5-Membered Heterocyclic Compounds as Antiviral Agents.
Curr Top Med Chem
; 23(7): 520-538, 2023.
Artículo
en Inglés
| MEDLINE | ID: covidwho-20243928
ABSTRACT
Viral infections range from self-limiting to more serious and fatal infections; therefore, some viral infections are of great public health concern worldwide, e.g., Hepatitis B virus, Hepatitis C virus, and HIV. Recently, the world faced a new infection due to the coronavirus, COVID-19, which was announced as a pandemic in early 2020. This virus infected more than 500 million people, killing around 6 million people worldwide. On the other hand, the increase in drug-resistant strains is also creating serious health problems. Thus, developing new selective antiviral agents with a different mode of action to fight against mutated and novel viruses is a primary goal of many researchers. Taking into account the role of heterocyclic compounds in drug discovery as a key structural component of most of the bioactive molecules; herein, we report an extensive review of the antiviral activity of five-membered heterocyclic compounds reported from 2015 to date. In this review, the antiviral activities of the agents containing the specified ring systems thiadiazoles, triazoles, oxadiazoles, and thiazoles are discussed.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Tiadiazoles
/
Virosis
/
COVID-19
/
Compuestos Heterocíclicos
Límite:
Humanos
Idioma:
Inglés
Revista:
Curr Top Med Chem
Asunto de la revista:
Química
Año:
2023
Tipo del documento:
Artículo
País de afiliación:
1568026623666230325153927
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