Concomitant Guillain-Barré syndrome and cerebral venous thrombosis complicating a SARS-CoV-2 infection: a case report.
Pan Afr Med J
; 42: 212, 2022.
Artículo
en Inglés
| MEDLINE | ID: covidwho-2025530
ABSTRACT
Cerebral venous thrombosis associated to acute inflammatory axonal polyneuropathy during infection with SARS-CoV-2 (coronavirus-2) is unusual. We describe the case of a 66-year-old patient with typical clinical and electrophysiological criteria of acute axonal motor neuropathy, who was positive for SARS-CoV-2. The symptoms started with fever associated with respiratory symptoms, and complicated one week later by headaches, and general weakness. The examination showed bilateral peripheral facial palsy, predominantly proximal tetraparesis, and areflexia with tingling of limbs were found. The whole was concomitant with the diagnosis of an acute polyradiculoneuropathy. Electrophysiologic evaluation confirmed the diagnosis. Cerebrospinal fluid examination showed albuminocytologic dissociation, and brain imaging revealed sigmoid sinus thrombophlebitis. Neurological manifestations improved during treatment with plasma exchange and anticoagulants. Our case draws attention to the occurrence of cerebral venous thrombosis and Guillain-Barré syndrome (GBS) in patients with COVID-19. The neuro-inflammation induced by the systemic immune response to infection, can lead to neurological manifestations. Further studies should be conducted on the full clinical spectrum of patients with COVID-19 with neurological symptoms.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Trombosis de la Vena
/
Parálisis de Bell
/
Síndrome de Guillain-Barré
/
Trombosis Intracraneal
/
COVID-19
Tipo de estudio:
Reporte de caso
/
Estudios diagnósticos
/
Estudio experimental
/
Estudio pronóstico
Tópicos:
Covid persistente
Límite:
Anciano
/
Humanos
Idioma:
Inglés
Revista:
Pan Afr Med J
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
Pamj.2022.42.212.31365
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