Diltiazem inhibits SARS-CoV-2 cell attachment and internalization and decreases the viral infection in mouse lung
Zhongguo Yufang Shouyi Xuebao / Chinese Journal of Preventive Veterinary Medicine
; 44(3):345-345, 2022.
Artículo
en Inglés, Chino
| CAB Abstracts | ID: covidwho-2034497
ABSTRACT
Since the outbreak of the new crown pneumonia, the new coronavirus (SARSCoV-2) has been mutating continuously, and it has now become prevalent in more than 200 countries. The cumulative number of confirmed cases in the world has exceeded 460 million, and the number of deaths has exceeded 6 million. The rapid mutation of SARS-CoV-2 highlights the importance of preventive and therapeutic drugs, however, effective therapeutic drugs for new coronary pneumonia are still very scarce. It is still the common goal of scientists from all over the world to develop a safe and effective drug for the treatment of new coronary pneumonia that can inhibit the infection of multiple SARS-CoV-2 mutant strains.
Pesticides and Drugs; Control [HH405]; Pesticides and Drugs; Chemistry and Formulation [HH420]; Prion, Viral, Bacterial and Fungal Pathogens of Animals [LL821]; Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Animal Models of Human Diseases [VV400]; Animal and in vitro Models for Pharmaceuticals [VV450]; antiviral agents; coronavirus disease 2019; disease models; dosage effects; drug development; drug therapy; efficacy; experimental infections; genes; human diseases; lungs; mutations; new drugs; pandemics; pathogenesis; pharmacodynamics; potency; safety; viral diseases; man; mice; Severe acute respiratory syndrome coronavirus 2; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Muridae; rodents; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; diltiazem; antivirals; chemotherapy; drug action; mechanism of drug action; SARS-CoV-2; viral infections
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Colección:
Bases de datos de organismos internacionales
Base de datos:
CAB Abstracts
Idioma:
Inglés
/
Chino
Revista:
Chinese Journal of Preventive Veterinary Medicine
Año:
2022
Tipo del documento:
Artículo
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