The relationship between cardiological parameters and PCR in patients with coronavirus infection: A cross-sectional study.
Medicine (Baltimore)
; 101(50): e31935, 2022 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: covidwho-2191099
ABSTRACT
Cardiovascular injuries induced by SARS CoV-2 have been reported repeatedly in various studies. Therefore, it is necessary to understand cardiac complications at a low cost, quickly. This study aimed to determine the relationship between cardiological parameters and polymerase chain reaction (PCR) in patients with coronavirus infection. Patients who were admitted to the emergency department due to the ongoing pandemic, all patients with similar symptoms to coronavirus disease 2019 infection were initially admitted to the respiratory emergency room and underwent subsequent evaluations to confirm or rule out SARS-COV2 infection symptoms were assessed for eligibility. Patient were categorized into 2 groups 1. Positive PCR and negative PCR groups. Binary logistic regression was performed to assess the effect of several factors on the likelihood of developing positive troponin, reduced ejection fraction (EF), and Positive brain natriuretic peptide (BNP). Among 195 patients included, 115 (58.9%) had positive PCR. Patient in the positive PCR and negative PCR were 58.04â
±â
18.03 and 59.19â
±â
15.38 years of age, respectively. Patients in the "positive PCR" were significantly less likely to have chronic kidney disease (6.69% vs 17.5%, P value .022), consume calcium channel blockers (6.69% vs 18.75%, P value0.012). At the univariable level, positive PCR was significantly associated with fewer odds for positive BNP (OR0.46, Pâ
=â
.019); nevertheless, the association was no longer significant after adjusting for confounders (adjusted OR0.56, Pâ
=â
.158). Unadjusted positive PCR results were not found to have a significant association with positive troponin or reduced EF. Likewise, multivariable regression revealed no association between positive PCR and positive troponin (aOR1.28, Pâ
=â
.529) and reduced EF (aOR0.65, Pâ
=â
.369). PCR positivity did not result in positive troponin and BNP and did not appear to decrease EF. In other words, serial troponin and BNP checks and initial echocardiography in coronavirus disease 2019 respiratory emergencies do not make significant differences in diagnostic and therapeutic management and inpatient outcomes of patients with positive or negative PCR and are not specific findings. Evidence suggests some coronavirus-induced cardiac complications will be manifested in the long term.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Disfunción Ventricular Izquierda
/
COVID-19
Tipo de estudio:
Estudios diagnósticos
/
Estudio experimental
/
Estudio observacional
/
Estudio pronóstico
/
Ensayo controlado aleatorizado
Tópicos:
Covid persistente
Límite:
Humanos
Idioma:
Inglés
Revista:
Medicine (Baltimore)
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
MD.0000000000031935
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