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Systemic Lupus Erythematosus Risk: The Role of Environmental Factors.
Liu, Jia Li; Woo, Jennifer M P; Parks, Christine G; Costenbader, Karen H; Jacobsen, Søren; Bernatsky, Sasha.
  • Liu JL; McGill University, Montreal, Quebec, Canada.
  • Woo JMP; Epidemiology Branch, Department of Health and Human Services, National Institutes of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
  • Parks CG; Epidemiology Branch, Department of Health and Human Services, National Institutes of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
  • Costenbader KH; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Jacobsen S; Copenhagen Lupus and Vasculitis Clinic, Rigshospitalet, Copenhagen University Hospital, Denmark.
  • Bernatsky S; Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. Electronic address: sasha.bernatsky@mcgill.ca.
Rheum Dis Clin North Am ; 48(4): 827-843, 2022 Nov.
Artículo en Inglés | MEDLINE | ID: covidwho-2232614
ABSTRACT
Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease. The etiology of SLE is multifactorial and includes potential environmental triggers, which may occur sequentially (the "multi-hit" hypothesis). This review focuses on SLE risk potentially associated with environmental factors including infections, the microbiome, diet, respirable exposures (eg, crystalline silica, smoking, air pollution), organic pollutants, heavy metals, and ultraviolet radiation.
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Exposición a Riesgos Ambientales / Lupus Eritematoso Sistémico Tipo de estudio: Estudio de etiologia / Estudio observacional / Estudio pronóstico Límite: Humanos Idioma: Inglés Revista: Rheum Dis Clin North Am Asunto de la revista: Reumatología Año: 2022 Tipo del documento: Artículo País de afiliación: J.rdc.2022.06.005

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Texto completo
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Exposición a Riesgos Ambientales / Lupus Eritematoso Sistémico Tipo de estudio: Estudio de etiologia / Estudio observacional / Estudio pronóstico Límite: Humanos Idioma: Inglés Revista: Rheum Dis Clin North Am Asunto de la revista: Reumatología Año: 2022 Tipo del documento: Artículo País de afiliación: J.rdc.2022.06.005