Probiotics and COVID-19: is there any link?
Lett Appl Microbiol
; 71(3): 229-234, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: covidwho-2248530
ABSTRACT
Understanding mechanisms of the novel SARS-CoV2 infection and progression can provide potential novel targets for prevention and/or treatment. This could be achieved via the inhibition of viral entry and/or replication, or by suppression of the immunologic response that is provoked by the infection (known as the cytokine storm). Probiotics are defined as 'live microorganisms that, when administered in adequate amounts, confer a health benefit on the host'. There is scarcity of evidence about the relationship between COVID-19 and gut microbiota. So, whether or not these supplements can prevent or ameliorate COVID-19-associated symptoms is not fully understood. The aim of this study is to provide an indirect evidence about the utility of probiotics in combating COVID-19 or its associated symptoms, through the review of its antiviral and anti-inflammatory properties in vitro, animal models and human trials. SIGNIFICANCE AND IMPACT OF THE STUDY The role of probiotics in alleviation of the novel COVID-19 has not been established. This review provides an insight about the anti-inflammatory, antiviral effects of probiotics in vitro, animal models and human. The latter can provide an indirect evidence and/or hypothesis-driven approach to investigate the use of probiotics as adjunctive therapy in the prophylaxis and/or alleviation of COVID-19 symptoms.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Probióticos
/
Microbioma Gastrointestinal
/
SARS-CoV-2
/
COVID-19
/
Antiinflamatorios
Tópicos:
Medicina tradicional
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Lett Appl Microbiol
Asunto de la revista:
Microbiologia
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Lam.13334
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