Macular optical coherence tomography angiography analysis in diabetes mellitus patients with a history of Covid-19.
Photodiagnosis Photodyn Ther
; 42: 103513, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: covidwho-2263189
ABSTRACT
PURPOSE:
There is evidence of decreased vessel density in optical coherence tomography angiography (OCTA) after Covid-19. We aimed to investigate whether the outcome of retinal vasculopathy would be worse if patients with diabetes mellitus (DM) were infected with coronavirus using OCTA to assess retinal vessels.METHODS:
One eye of each subject was included in the study. Diabetic patients without retinopathy and non-diabetic controls were divided into four groups according to their Covid-19 history group 1=DM(-)Covid-19(-); group 2=DM(+)Covid-19(-); group 3=DM(-)Covid-19(+); and group 4=DM(+)Covid-19(+). All Covid-19 patients were not hospitalised. Macular OCTA scans were performed in a 6 × 6 mm area.RESULTS:
Diabetes had no effect on the area of the foveal avascular zone (FAZ), but Covid-19 caused an increase in FAZ area. Diabetes and Covid-19 had an effect on both the superficial capillary plexus (SCP) and the deep capillary plexus (DCP) in the fovea. Eta squared (Æ2) is a measure of effect size. The effect size of Covid-19 (Æ2=0.180) was found to be greater than that of diabetes (Æ2=0.158) on the SCP, whereas the effect size of diabetes (Æ2=0.159) was found to be greater than that of Covid-19 (Æ2=0.091) on the DCP.CONCLUSIONS:
The percentage of vessel density was lower in the fovea and the FAZ area was enlarged in the diabetic patients who recovered from Covid-19. In diabetic patients Covid-19 may lead to deterioration of vascular metrics.Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Fotoquimioterapia
/
Diabetes Mellitus
/
Retinopatía Diabética
/
COVID-19
Tipo de estudio:
Estudio experimental
/
Estudio pronóstico
/
Ensayo controlado aleatorizado
Límite:
Humanos
Idioma:
Inglés
Revista:
Photodiagnosis Photodyn Ther
Asunto de la revista:
Diagnóstico por Imagen
/
Terapeutica
Año:
2023
Tipo del documento:
Artículo
País de afiliación:
J.pdpdt.2023.103513
Similares
MEDLINE
...
LILACS
LIS