Obesity: A critical risk factor in the COVID-19 pandemic.
Clin Obes
; 10(6): e12403, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: covidwho-2267680
ABSTRACT
Obesity is an emerging independent risk factor for susceptibility to and severity of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Previous viral pandemics have shown that obesity, particularly severe obesity (BMI > 40 kg/m2 ), is associated with increased risk of hospitalization, critical care admission and fatalities. In this narrative review, we examine emerging evidence of the influence of obesity on COVID-19, the challenges to clinical management from pulmonary, endocrine and immune dysfunctions in individuals with obesity and identify potential areas for further research. We recommend that people with severe obesity be deemed a vulnerable group for COVID-19; clinical trials of pharmacotherapeutics, immunotherapies and vaccination should prioritize inclusion of people with obesity.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Neumonía Viral
/
Infecciones por Coronavirus
/
Obesidad
Tipo de estudio:
Estudio pronóstico
/
Ensayo controlado aleatorizado
/
Revisiones
Tópicos:
Covid persistente
/
Vacunas
Límite:
Humanos
Idioma:
Inglés
Revista:
Clin Obes
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Cob.12403
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