Clinical characteristics and 12-month outcomes of patients with myocardial infarction with nonobstructive coronary arteries before and during the COVID-19 pandemic.
Pol Arch Intern Med
; 133(5)2023 05 23.
Artículo
en Inglés
| MEDLINE | ID: covidwho-2307563
ABSTRACT
INTRODUCTION:
SARSCoV2 infection is associated with an increased risk of thromboembolic complications. Thromboembolism is one of the possible causes of myocardial infarction with nonobstructive coronary arteries (MINOCA).OBJECTIVES:
We aimed to compare the characteristics and 12month clinical outcomes of patients with MINOCA treated before and during the COVID19 pandemic. PATIENTS ANDMETHODS:
We retrospectively analyzed data of 51 734 patients with acute myocardial infarction registered in the nationwide Polish Registry of Acute Coronary Syndromes database in 2019 and 2020. The final study group included 3178 patients with MINOCA. We compared the baseline characteristics, management strategies, and 12month clinical outcomes of the MINOCA patients treated before (2019) and during the COVID19 pandemic (2020).RESULTS:
The rate of MINOCA was higher in 2019 than in 2020 (6.3% vs 5.9%; P = 0.03). The only difference between the groups was a higher hypercholesterolemia rate before the pandemic (33.9% vs 28.2%; P <0.001). Inhospital stroke was observed more frequently during the pandemic (0% vs 0.3%; P = 0.01), whereas other inhospital complications were similar between the groups. Most patients were discharged on aspirin (85.6%), a ßblocker (73.1%), an angiotensinconverting enzyme inhibitor / angiotensin receptor blocker (70.2%), and a statin (62.7%), but only 50.6% of the participants received a P2Y12 inhibitor. There was no difference in 12month allcause mortality between the patients with MINOCA treated before and during the pandemic (9.2% vs 11%; P = 0.09).CONCLUSIONS:
We observed a lower percentage of MINOCA cases and higher inhospital stroke rates in the MINOCA patients treated during the COVID19 pandemic (2020). The possible association between worse clinical outcomes of the MINOCA patients treated during the pandemic and the increased risk for thromboembolic complications of SARSCoV2 infection needs further evaluation.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Accidente Cerebrovascular
/
COVID-19
/
Infarto del Miocardio
Tipo de estudio:
Estudio experimental
/
Estudio observacional
/
Estudio pronóstico
/
Ensayo controlado aleatorizado
Tópicos:
Covid persistente
Límite:
Humanos
Idioma:
Inglés
Año:
2023
Tipo del documento:
Artículo
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