Advances and challenges in neuropathic pain: a narrative review and future directions.
Br J Anaesth
; 131(1): 79-92, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: covidwho-2321754
ABSTRACT
Over the past few decades, substantial advances have been made in neuropathic pain clinical research. An updated definition and classification have been agreed. Validated questionnaires have improved the detection and assessment of acute and chronic neuropathic pain; and newer neuropathic pain syndromes associated with COVID-19 have been described. The management of neuropathic pain has moved from empirical to evidence-based medicine. However, appropriately targeting current medications and the successful clinical development of drugs acting on new targets remain challenging. Innovative approaches to improving therapeutic strategies are required. These mainly encompass rational combination therapy, drug repurposing, non-pharmacological approaches (such as neurostimulation techniques), and personalised therapeutic management. This narrative review reports historical and current perspectives regarding the definitions, classification, assessment, and management of neuropathic pain and explores potential avenues for future research.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
COVID-19
/
Neuralgia
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Revisiones
Límite:
Humanos
Idioma:
Inglés
Revista:
Br J Anaesth
Año:
2023
Tipo del documento:
Artículo
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