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Lipase Elevation in Patients With COVID-19.
McNabb-Baltar, Julia; Jin, David X; Grover, Amit S; Redd, Walker D; Zhou, Joyce C; Hathorn, Kelly E; McCarty, Thomas R; Bazarbashi, Ahmad N; Shen, Lin; Chan, Walter W.
  • McNabb-Baltar J; Division of Gastroenterology, Hepatology, and Endoscopy, Center for Pancreatic Disease, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Jin DX; Harvard Medical School, Boston, Massachusetts, USA.
  • Grover AS; Division of Gastroenterology, Hepatology, and Endoscopy, Center for Pancreatic Disease, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Redd WD; Harvard Medical School, Boston, Massachusetts, USA.
  • Zhou JC; Harvard Medical School, Boston, Massachusetts, USA.
  • Hathorn KE; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Program for Pancreatic Disorders, Boston, Massachusetts, USA.
  • McCarty TR; Harvard Medical School, Boston, Massachusetts, USA.
  • Bazarbashi AN; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
  • Shen L; Harvard Medical School, Boston, Massachusetts, USA.
  • Chan WW; Harvard Medical School, Boston, Massachusetts, USA.
Am J Gastroenterol ; 115(8): 1286-1288, 2020 08.
Artículo en Inglés | MEDLINE | ID: covidwho-2324863
ABSTRACT

INTRODUCTION:

Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19.

METHODS:

A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19.

RESULTS:

Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms.

DISCUSSION:

Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Pancreatitis / Neumonía Viral / Infecciones por Coronavirus / Lipasa Tipo de estudio: Estudio de cohorte / Estudio observacional / Estudio pronóstico Límite: Anciano / Femenino / Humanos / Masculino / Middle aged País/Región como asunto: America del Norte Idioma: Inglés Revista: Am J Gastroenterol Año: 2020 Tipo del documento: Artículo País de afiliación: Ajg.0000000000000732

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Pancreatitis / Neumonía Viral / Infecciones por Coronavirus / Lipasa Tipo de estudio: Estudio de cohorte / Estudio observacional / Estudio pronóstico Límite: Anciano / Femenino / Humanos / Masculino / Middle aged País/Región como asunto: America del Norte Idioma: Inglés Revista: Am J Gastroenterol Año: 2020 Tipo del documento: Artículo País de afiliación: Ajg.0000000000000732