A new outbreak of HIV infection among people who inject drugs during the COVID-19 pandemic in Greece.
Int J Drug Policy
; 117: 104073, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: covidwho-2326552
ABSTRACT
BACKGROUND:
Multiple HIV outbreaks have been recorded among people who inject drugs (PWID) since 2010. During an intervention for PWID in 2019-2021 in Thessaloniki, Greece, an increasing number of HIV cases was documented. Here, we provide an analysis of this new outbreak.METHODS:
ALEXANDROS was a community-based program and participation included interviewing, rapid HIV/HCV tests, counselling and linkage to care. PWID were recruited through Respondent-Driven Sampling (RDS) in five sampling rounds. Crude and RDS-weighted HIV prevalence estimates were obtained. HIV incidence was estimated from data on 380 initially seronegative PWID with at least two tests. Multivariable Cox proportional hazards model was used to assess risk factors for HIV seroconversion.RESULTS:
In total, 1,101 PWID were recruited. At first participation, 53.7% were current PWID, 20.1% homeless, 20.3% on opioid substitution treatment and 4.8% had received syringes in the past 12 months. HIV prevalence (95% CI) was 7.0% (5.6-8.7%) and an increasing trend was observed over 2019-2021 (p = 0.002). Two-thirds of the cases (67.5%) were new diagnoses. HIV incidence was 7.0 new infections/100 person-years (95% CI4.8-10.2). Homelessness in the past 12 months (HR2.68; 95% CI1.24-5.81) and receptive syringe sharing (HR3.86; 95% CI1.75-8.51) were independently associated with increased risk of seroconversion. By the end of the program, 67.3% of the newly diagnosed cases initiated antiretroviral treatment.CONCLUSIONS:
A new HIV outbreak among PWID was documented in Greece during the COVID-19 pandemic with homelessness and syringe sharing being associated with increased risk of HIV acquisition. Peer-driven programs targeting the population of high-risk underserved PWID can be used to early identify emerging outbreaks and to improve linkage to HIV care.Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Infecciones por VIH
/
Abuso de Sustancias por Vía Intravenosa
/
Seropositividad para VIH
/
Consumidores de Drogas
/
COVID-19
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
País/Región como asunto:
Europa
Idioma:
Inglés
Revista:
Int J Drug Policy
Asunto de la revista:
Salud Pública
/
Trastornos Relacionados con Sustancias
Año:
2023
Tipo del documento:
Artículo
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