Diagnosis for COVID-19

ABSTRACT

"COVID-2019,” a recently emerged novel coronavirus disease, is causing serious health issues to the public and becoming more and more fatal every next day. On December 31, 2019, low respiratory infection cases were detected in Wuhan, China, which is in China's Hubei province. The cases were reported to the WHO Office of China and they could not identify the agents for the cause. The first cases were classified to be "pneumonia of unknown etiology.” The investigation program was initiated by the Chinese Center for Disease Control and Prevention (CDC). The etiology of the disease was attributed to a novel virus of the coronavirus (CoV) family. Dr. Tedros Adhanom Ghebreyesus, WHO Director-General, called the disease caused by this CoV the "COVID-19,” which is an acronym for "coronavirus disease 2019.” It is found that "COVID-19” is caused by bête-coronavirus named "severe acute coronavirus-2” (SARS-CoV-2). It belongs to those virus families that appear as pneumonia in the human body. It affects the lower respiratory tract badly. This virus has been identified as another version of the family of severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) [1, 2]. SARS-CoV-2, SARS-CoV, and MERS-CoV possess similarity with them. They have differences in genotypic and phenotypic structure that guide their pathogenesis. So far, as per the findings, this virus originated in bats. It reached humans through contact with unknown animals. The transmission of this virus among humans is via direct contacts, inhalation of infected droplets, and contaminated hands and surfaces. Some of the symptoms of this disease are cough, sore cough, fever, fatigue, and dyspnea/breathlessness. The remedy of this disease is to diagnose the infection at the initial stage, supportive treatment to survive, self-quarantines, mass-quarantines, etc. This paper presents a systematic review of the origin of coronavirus, its types, transmissions, symptoms, and the current developments in diagnosing testing and vaccine trials. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.