MRI of fatal course of acute hemorrhagic leukoencephalitis in a child with SARS-CoV-2 omicron BA 2.0 infection.
Neuroradiology
; 65(7): 1179-1181, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: covidwho-2327104
ABSTRACT
We present a pediatric case of acute hemorrhagic leukoencephalitis associated with SARS-CoV-2 Omicron BA 2.0 infection. A previously healthy girl presented with ataxia and diplopia three weeks after the COVID-19 confirmation from a nasopharyngeal swab. Acute and symmetrical motor weakness and drowsiness ensued within the following 3 days. She then became spastic tetraplegic. MRI revealed multifocal lesions in the cerebral white matter, basal ganglia, and brainstem, with hemorrhagic changes confirmed with T1-hyperintensity and hypointensity on susceptibility-weighted images. Peripheral areas of decreased diffusion, increased blood flow, and rim contrast enhancement were noted in the majority of lesions. She was treated with a combination of intravenous immunoglobulin and methylprednisolone pulse therapy. Neurological deterioration ensued with coma, ataxic respiratory pattern and decerebrate posture. Repeated MRI performed on day 31 revealed progression of abnormalities, hemorrhages and brain herniation. Despite the administration of plasma exchange, she died two months after admission.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Leucoencefalitis Hemorrágica Aguda
/
COVID-19
Tipo de estudio:
Estudio pronóstico
Tópicos:
Covid persistente
/
Variantes
Límite:
Niño
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Neuroradiology
Año:
2023
Tipo del documento:
Artículo
País de afiliación:
S00234-023-03160-7
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