First report of manic-like symptoms in a COVID-19 patient with no previous history of a psychiatric disorder.
J Affect Disord
; 277: 337-340, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: covidwho-722855
ABSTRACT
BACKGROUND:
In December 2019, the novel coronavirus (SARS-CoV-2) infection was first reported in Wuhan city, central China, which has spread rapidly. The common clinical features of patients with SARS-CoV-2 infection included fever, fatigue, and damage to the respiratory or digestive system. However, it is still unclear whether SARS-CoV-2 infection could cause damage to the central nervous system (CNS) inducing psychiatric symptoms. CASE REPORT Herein, we present the first case of SARS-CoV-2 infection with manic-like symptoms and describe the diagnosis, clinical course, and treatment of the case, focusing on the identifications of SARS-CoV-2 in the specimen of cerebrospinal fluid (CSF). The patient developed manic-like symptoms when his vital signs recovered on illness day 17. After manic-like attack, the detection of SARS-CoV-2 specific IgG antibody in CSF was positive, while the reverse transcriptase-polymerase chain reaction (RT-PCR) on CSF for the SARS-CoV-2 was negative. The patient received Olanzapine for treatment and his mood problems concurrently improved as indicated by scores of Young Manic Rating Scale (YMRS).LIMITATION:
This is a single case report only, and the RT-PCR test for SARS-CoV-2 in CSF was not performed simultaneously when SARS-CoV-2 was positive in samples of sputum and stool.CONCLUSION:
This first case of COVID-19 patient with manic-like symptoms highlights the importance of evaluation of mental health status and may contribute to our understanding of potential risk of CNS impairments by SARS-CoV-2 infection.Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Neumonía Viral
/
Trastorno Bipolar
/
Infecciones por Coronavirus
Tipo de estudio:
Reporte de caso
/
Estudios diagnósticos
/
Estudio experimental
/
Estudio pronóstico
Tópicos:
Covid persistente
/
Variantes
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
J Affect Disord
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
J.jad.2020.08.031
Similares
MEDLINE
...
LILACS
LIS