Establishment of a rapid diagnosis assay for SARS-CoV-2 infection based on MALDI-TOF MS

Xiao, Di, Qin, Tian, Hou, XueXin, Gao, ZhenGuo, Wang, JiTao, Zhang, HuiFang, Zhang, BingHua, Li, MingHui, Sun, JingXuan, Wang, Lei, Yang, WenTao, Li, TianYi, Muti, Mahe, Lu, JinXing

Xiao, Di, Qin, Tian, Hou, XueXin, Gao, ZhenGuo, Wang, JiTao, Zhang, HuiFang, Zhang, BingHua, Li, MingHui, Sun, JingXuan, Wang, Lei, Yang, WenTao, Li, TianYi, Muti, Mahe, Lu, JinXing.

Disease Surveillance ; 36(11):1196-1202, 2021.

Article Dans Chinois | CAB Abstracts | ID: covidwho-1726085

ABSTRACT

ABSTRACT

Objective:

To establish a rapid, high-throughput detection assay of serum peptidome profiling for the diagnosis of SARS-CoV-2 infection based on matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS).

Mots clés

Diagnosis of Human Disease [VV720]; Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Mathematics and Statistics [ZZ100]; blood serum; diagnosis; diagnostic techniques; coronavirus disease 2019; viral diseases; pandemics; public health; human diseases; rapid methods; MALDI-TOF; mass spectrometry; assays; detection; algorithms; molecular genetics techniques; mathematical models; polypeptides; screening; diagnostic value; biochemical markers; accuracy; biosafety; Severe acute respiratory syndrome coronavirus 2; man; Beijing; China; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Northern China; APEC countries; East Asia; Asia; high Human Development Index countries; upper-middle income countries; SARS-CoV-2; viral infections; matrix-associated laser desorption ionization time of flight mass spectrometry; screening tests; biomarkers; Peking; People's Republic of China

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Texte intégral: Disponible Collection: Bases de données des oragnisations internationales Base de données: CAB Abstracts langue: Chinois Revue: Disease Surveillance Année: 2021 Type de document: Article

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