Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants

Zhang, Yali, Wei, Min, Wu, Yangtao, Wang, Juan, Hong, Yuting, Huang, Yang, Yuan, Lunzhi, Ma, Jian, Wang, Kai, Wang, Shaojuan, Shi, Yang, Wang, Zikang, Guo, Huilin, Xiao, Jin, Yang, Chuanlai, Ye, Jianghui, Chen, Jijing, Liu, Yuxi, Fu, Baorong, Lan, Miaolin, Gong, Peixuan, Huang, Zehong, Su, Yingying, Chen, Yixin, Zhang, Tianying, Zhang, Jun, Zhu, Huachen, Yu, Hai, Yuan, Quan, Cheng, Tong, Guan, Yi, Xia, Ningshao

Zhang, Yali, Wei, Min, Wu, Yangtao, Wang, Juan, Hong, Yuting, Huang, Yang, Yuan, Lunzhi, Ma, Jian, Wang, Kai, Wang, Shaojuan, Shi, Yang, Wang, Zikang, Guo, Huilin, Xiao, Jin, Yang, Chuanlai, Ye, Jianghui, Chen, Jijing, Liu, Yuxi, Fu, Baorong, Lan, Miaolin, Gong, Peixuan, Huang, Zehong, Su, Yingying, Chen, Yixin, Zhang, Tianying, Zhang, Jun, Zhu, Huachen, Yu, Hai, Yuan, Quan, Cheng, Tong, Guan, Yi, Xia, Ningshao.

Cell reports ; 2022.

Article Dans Anglais | EuropePMC | ID: covidwho-1728589

ABSTRACT

ABSTRACT

Zhang et al. show in vitro cross-species infectivity and neutralization-escape characteristics of 153 SARS-CoV-2 RBD mutants and 11 globally circulating VOC/VOI variants. They reveal an association between enhanced cross-species infection potential and the current cumulative prevalence of mutations, which can inform surveillance and forecasting of SARS-CoV-2 spike mutations.

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Collection: Bases de données des oragnisations internationales Base de données: EuropePMC Type d'étude: Essai contrôlé randomisé Les sujets: Variantes langue: Anglais Revue: Cell reports Année: 2022 Type de document: Article

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