COVID-19 Incidence and its Clinical Course in Liver Transplant Recipients.
Kanzo/Acta Hepatologica Japonica
; 63(6):293-296, 2022.
Article
Dans Japonais
| EMBASE | ID: covidwho-20239409
ABSTRACT
Organ transplant recipients receive immunosuppressive drugs and hence are at high risk for COVID-19 due to their compromised immunity. This study assessed 1,370 liver transplant recipients who were followed at our hospital. A total of 12 patients got COVID-19 5 recipients <50-years-old had mild disease, 7 recipients >60-years-old had moderate to severe disease, and 2 patients died. In addition, not all patients received 2 vaccinations, suggesting that the immunization is important for COVID-19 prophylaxis even in this patient population. One recipient was successfully treated with a combination of a reduced dose of immunosuppressive drugs, dexamethasone, remdesivir, and antibiotics, which is being established as an effective therapy for COVID-19.Copyright © 2022 The Japan Society of Hepatology.
covid-19; COVID-19 vaccination; Liver transplantation; adult; article; controlled study; coronavirus disease 2019/dt [Drug Therapy]; coronavirus disease 2019/ep [Epidemiology]; disease course; drug dose reduction; graft recipient; Hepatitis B virus; human; immunization; incidence; liver cell carcinoma; liver graft; major clinical study; middle aged; prophylaxis; Severe acute respiratory syndrome coronavirus 2; vaccination; antibiotic agent/cb [Drug Combination]; antibiotic agent/dt [Drug Therapy]; dexamethasone/cb [Drug Combination]; dexamethasone/dt [Drug Therapy]; immunosuppressive agent/cb [Drug Combination]; immunosuppressive agent/dt [Drug Therapy]; immunosuppressive agent/pv [Special Situation for Pharmacovigilance]; remdesivir/cb [Drug Combination]; remdesivir/dt [Drug Therapy]; SARS-CoV-2 vaccine/dt [Drug Therapy]
Texte intégral:
Disponible
Collection:
Bases de données des oragnisations internationales
Base de données:
EMBASE
Type d'étude:
Étude observationnelle
/
Étude pronostique
Les sujets:
Vaccins
langue:
Japonais
Revue:
Acta Hepatologica Japonica
Année:
2022
Type de document:
Article
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