Frequency of Diabetes Mellitus and Newly Diagnosed Hyperglycemia and Their Impacts on Hospitalized COVID-19 Patients
Shiraz E Medical Journal
; 24(4) (no pagination), 2023.
Article
Dans Anglais
| EMBASE | ID: covidwho-20241778
ABSTRACT
Background:
The coronavirus disease 2019 (COVID-19) pandemic and its associated morbidities are a great global concern. Diabetes mellitus (DM) is associated with adverse clinical outcomes and high mortality in patients with COVID-19. Objective(s) This study examined the frequency of BM, newly diagnosed hyperglycemia, and their impacts on hospitalized patients with COVID-19. Method(s) This retrospective study examined 810 medical records of PCR-confirmed COVID-19 patients admitted to Razi Hospital, Ahvaz, Iran. The clinical presentations, severity, and impacts of COVID-19 were compared between patients with and without DM. Disease severity was determined based on the NEWS2 scoring system. Result(s) This study included 810 medical records of COVID-19 patients, of whom 326 had pre-existing DM, and 484 were non-DM. The rates of diabetes and newly diagnosed hyperglycemia were 40.2% and 11.2%, respectively. The most common underlying diseases were hypertension (35.3%), ischemic heart disease (17.9%), and chronic kidney disease (11.9%), which were higher in people with diabetes than non-diabetics. The rate of acute kidney injury was higher in patients with diabetes than in non-diabetics (30.7% vs. 19.2%;P < 0.001) and in patients with severe COVID-19 than in those whose disease was not severe (27.8% vs. 21.5%;P = 0.04). The rates of severe COVID-19 (46.3% vs. 34.7%;P = 0.093), ICU admission (40.7% vs. 27.4%;P = 0.012), and mortality (18.5% vs. 10.5%;P = 0.079) were higher in patients with newly diagnosed hyperglycemia than in euglycemic patients. Conclusion(s) This study showed that COVID-19 infection is linked with newly diagnosed hyperglycemia and pre-existing DM, both associated with severe COVID-19, more need for ICU admission, and mortality.Copyright © 2023, Author(s).
covid-19; Diabetes Mellitus; Mortality; Newly Diagnosed Hyperglycemia; acute kidney failure; adult; anorexia; article; cardiovascular disease; chronic kidney failure; clinical feature; computer assisted tomography; coronavirus disease 2019; coughing; cross-sectional study; diabetic ketoacidosis; disease duration; disease severity; dyspnea; female; fever; ground glass opacity; headache; hemoptysis; hospital admission; hospital patient; human; hyperglycemia; hypertension; immunoturbidimetry; intensive care unit; Iran; ischemic heart disease; length of stay; loss of appetite; lung consolidation; male; middle aged; morbidity; myalgia; National Early Warning Score 2; retrospective study; reverse transcription polymerase chain reaction; risk factor; creatinine/ec [Endogenous Compound]; glucose/ec [Endogenous Compound]; hemoglobin A1c/ec [Endogenous Compound]
Texte intégral:
Disponible
Collection:
Bases de données des oragnisations internationales
Base de données:
EMBASE
Type d'étude:
Études expérimentales
/
Étude observationnelle
/
Étude pronostique
langue:
Anglais
Revue:
Shiraz E Medical Journal
Année:
2023
Type de document:
Article
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