Characteristics of liver injury in cases of COVID-19.
Kanzo/Acta Hepatologica Japonica
; 62(6):381-383, 2021.
Article
Dans Japonais
| EMBASE | ID: covidwho-20244958
ABSTRACT
In novel coronavirus disease 2019 (COVID-19), liver injury was found at a high rate, and reports from outside Japan revealed that such injury was related to severity. We examined the characteristics of liver injury in 15 cases of COVID-19. Thirteen of these patients received antiviral therapy, such as favipiravir, remdesivir, and hydroxychloroquine. Liver injury was observed in eight cases at admission for COVID-19. The hepatic CT attenuation values at admission were significantly lower in nine patients who developed liver damage or showed its exacerbation during the treatment than in the remaining patients. Drug-induced liver injury due to antiviral drug was suspected in six cases. Liver injury due to COVID-19 may be related to low hepatic CT attenuation values and be modified by antiviral drugs.Copyright © 2021 The Japan Society of Hepatology.
covid-19; Hepatic CT value; Liver injury; antiviral therapy; article; clinical article; computer assisted tomography; coronavirus disease 2019/dt [Drug Therapy]; disease exacerbation; drug-induced liver injury/si [Side Effect]; human; favipiravir/ae [Adverse Drug Reaction]; favipiravir/dt [Drug Therapy]; hydroxychloroquine/ae [Adverse Drug Reaction]; hydroxychloroquine/dt [Drug Therapy]; remdesivir/ae [Adverse Drug Reaction]; remdesivir/dt [Drug Therapy]
Texte intégral:
Disponible
Collection:
Bases de données des oragnisations internationales
Base de données:
EMBASE
Type d'étude:
Étude pronostique
langue:
Japonais
Revue:
Acta Hepatologica Japonica
Année:
2021
Type de document:
Article
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