Application of 4-aminoquinoline antimalarial drugs in virus infection

ABSTRACT

A number of in Vitro experiments and clinical studies have shown that classical quinoline antimalarial drugs such as quinine, chloroquine, hydroxychloroquine, mefloquine, not only have anti-plasmodial effects, but also have a wide range of antiviral effects against influenza Virus, hepatitis Virus, yellow fever virus, human immunodeficiency Virus and coronavirus infections. This review briefly describes the research advances and clinical application of the antiviral effects of 4- aminoquinoline drugs, hoping to provide useful information for in-depth research and utilization of anti-malarial drugs for combating Virus infections.