Stimuli-responsive hydrogels for cancer immunotherapy
Polymer Chemistry
; 2023.
Article
Dans Anglais
| Web of Science | ID: covidwho-2244412
ABSTRACT
Immunotherapy plays an important role in cancer treatment by activating or suppressing the immune system. However, there are still a series of challenges to overcome regarding the delivery vehicles of immunotherapeutic agents and their effective activation at tumor sites. Meanwhile, owing to their well-hydrated environment and capability of immobilizing biological cargos, hydrogels in combination with immunotherapies provide a chance to enhance the antitumor immune response with reduced side effects. In addition, stimuli-responsiveness has been also widely applied to optimize the pharmacokinetics with an improved therapeutic outcome. In this review, we discuss the opportunities for the combination of immunotherapy and stimuli-responsive hydrogels, such as light, temperature, ultrasound and magnetically responsive hydrogels, for effective cancer treatment. Finally, we explore the potential of stimuli-responsive hydrogels as vaccine implants against cancer and Covid-19.
Texte intégral:
Disponible
Collection:
Bases de données des oragnisations internationales
Base de données:
Web of Science
langue:
Anglais
Revue:
Polymer Chemistry
Année:
2023
Type de document:
Article
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