Evaluation of Inosine-Acedoben-Dimepranol as an immunomodulator in broiler chicks vaccinated with Infectious bronchitis virus vaccine
Benha Veterinary Medical Journal
; 42(2):99-103, 2022.
Article
Dans Anglais
| CAB Abstracts | ID: covidwho-2262395
ABSTRACT
Protecting livestock against diseases by enhancing its immunity is essential and required in poultry industry. Therefore, the aim of the present study was to evaluate the possible immunoenhancing effects of Inosine-Acedoben-Dimepranol (IAD) in broiler chicks. A total of 150 chicks were used in the present study, divided into 6 groups (25 for each) and subjected to different treatments. It has been found that IAD significantly (P 0.05) increased total leukocytic count, with increased granulocyte (neutrophils, eosinophils, basophils), lymphocyte and monocyte counts compared to control chicks. IAD significantly (P 0.05) increased total protein as a result of increased globulins in plasma when compared with those of control. IAD has been found to significantly (P 0.05) increase immune response of IB vaccine in IAD + IB vaccine-treated groups compared to control measured by ELISA. IAD exhibited antiviral effect indicated by increased survival percent of chicks challenged with virulent IB virus with survival 100% in the groups received IAD large dose plus vaccine. Data of the present study may indicate that supplying chicks with IAD in drinking water is a good recommendation in poultry industry based on its immune enhancing properties.
Prion; Viral; Bacterial and Fungal Pathogens of Animals [LL821], Animal Immunology [LL650], Host Resistance and Immunity [HH600], chicks, broilers, immune response, inosine, immunomodulators, leukocyte count, neutrophils, eosinophils, basophils, lymphocytes, monocytes, drinking water, vaccination, disease prevention, disease control, poultry, avian infectious bronchitis, fowls, Infectious bronchitis virus, Gallus gallus, Gallus, Phasianidae, Galliformes, birds, vertebrates, Chordata, animals, eukaryotes, Avian coronavirus, Gammacoronavirus, Coronavirinae, Coronaviridae, Nidovirales, positive-sense ssRNA Viruses, ssRNA Viruses, RNA Viruses, viruses, acedoben, dimepranol, chickens, immunity reactions, immunological reactions, IBV infection, cell count, eosinophil leukocytes, domesticated birds
Texte intégral:
Disponible
Collection:
Bases de données des oragnisations internationales
Base de données:
CAB Abstracts
Type d'étude:
Études expérimentales
Les sujets:
Vaccins
langue:
Anglais
Revue:
Benha Veterinary Medical Journal
Année:
2022
Type de document:
Article
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