One-year temporal changes in long COVID prevalence and characteristics: a systematic review and meta-analysis.
Value Health
; 2022 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: covidwho-20237002
ABSTRACT
OBJECTIVES:
This study aimed to explore the 1-year temporal change in prevalence, variety, and potential risk factors of long COVID symptoms, and to further predict the prognostic trends of long COVID.METHODS:
We searched electronic databases for related studies published from January 2020 to February 2022, and conducted one group meta-analysis and locally weighted regression explore the monthly temporal change in the prevalence of each long COVID symptom in 1-year follow-up period.RESULTS:
A total of 137 studies were included in meta-analysis, including 134,093 participants. The temporal change of any long COVID symptom showed a steep decrease initially (from 92% at acute phase to 55% at 1-month follow-up), followed by stabilization at approximately 50% during 1-year follow-up. Six months or more after the acute phase, the odds ratio (OR) of population characteristic factors increased, such as female gender (from 1.62 to 1.82), while the OR value of acute phase-related factors (severe/critical and hospitalization) decreased. As for specific symptoms, about two-thirds of the symptoms did not significantly reduce during the 1-year follow-up, and the neuropsychiatric symptoms showed a higher long-term prevalence (approximately 25%) and longer persistence than physical-symptoms.CONCLUSIONS:
The temporal changes in the prevalence and characteristics speculate that long COVID may persist longer than expected. In particular, we should pay more attention to neuropsychiatric symptoms and other symptoms for which there is no significant downward trend in prevalence. The influence of acute phase-related factors for long COVID gradually decreases over time, while the influence of population characteristic-related gradually increases.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MEDLINE
Tipo de estudo:
Estudo de coorte
/
Estudo observacional
/
Estudo prognóstico
/
Revisões
/
Revisão sistemática/Meta-análise
Tópicos:
Covid persistente
Idioma:
Inglês
Assunto da revista:
Farmacologia
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
J.jval.2022.11.011
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