Assessment of basic reproductive number for COVID-19 at global level: A meta-analysis.
Medicine (Baltimore)
; 100(18): e25837, 2021 May 07.
Artigo
em Inglês
| MEDLINE | ID: covidwho-2191001
ABSTRACT
BACKGROUND:
There are large knowledge gaps regarding how transmission of 2019 novel coronavirus disease (COVID-19) occurred in different settings across the world. This study aims to summarize basic reproduction number (R0) data and provide clues for designing prevention and control measures.METHODS:
Several databases and preprint platforms were retrieved for literature reporting R0 values of COVID-19. The analysis was stratified by the prespecified modeling method to make the R0 values comparable, and by country/region to explore whether R0 estimates differed across the world. The average R0 values were pooled using a random-effects model.RESULTS:
We identified 185 unique articles, yielding 43 articles for analysis. The selected studies covered 5 countries from Asia, 5 countries from Europe, 12 countries from Africa, and 1 from North America, South America, and Australia each. Exponential growth rate model was most favored by researchers. The pooled global R0 was 4.08 (95% CI, 3.09-5.39). The R0 estimates for new and shifting epicenters were comparable or even higher than that for the original epicenter Wuhan, China.CONCLUSIONS:
The high R0 values suggest that an extraordinary combination of control measures is needed for halting COVID-19.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
/
Saúde Global
/
Número Básico de Reprodução
/
COVID-19
Tipo de estudo:
Estudo observacional
/
Ensaios controlados aleatorizados
/
Revisões
Limite:
Humanos
Idioma:
Inglês
Revista:
Medicine (Baltimore)
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
MD.0000000000025837
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