Influence of influenza vaccine and comorbidity on the evolution of hospitalized COVID-19 patients. / Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19.
Med Clin (Barc)
; 158(12): 603-607, 2022 06 24.
Artigo
em Inglês, Espanhol
| MEDLINE | ID: covidwho-2308996
ABSTRACT
BACKGROUND AND OBJECTIVE:
The COVID-19 coronavirus disease outbreak is evolving around the world. The aim of this study is to evaluate the association between influenza vaccination and the risk of mortality in hospitalized COVID-19 patients, as well as other risk factors. MATERIALS ANDMETHODS:
Retrospective observational study. This study was conducted among hospitalized patients with COVID-19 at Hospital La Mancha Centro between March 5 and 25, 2020. Information on influenza vaccination was extracted from electronic medical records. We used a multivariate logistic regression to explore the association between influenza vaccination and mortality from COVID and other risk factors.RESULTS:
410 patients were included. Influenza vaccine had no effect among COVID-19 hospitalized patients [OR 1.55 (95%CI 0.96 - 2.48; p=0.071)]. Increasing hospital mortality was associated with older age [OR 1.05 (95% CI 1.02-1.07), per year increase; p<0.001)], Charlson ≥3 [OR 1.84 (95%CI 1.07-3.15, p=0.027)] and heart failure on admission [OR 6 (IC95% 1.6 - 21.7; p=0.007)]CONCLUSIONS:
Influenza vaccine had no effect among COVID-19 hospitalized patients. The risk factors identified were older age, higher comorbidity and heart failure on admission.Palavras-chave
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MEDLINE
Assunto principal:
Vacinas contra Influenza
/
Influenza Humana
/
COVID-19
/
Insuficiência Cardíaca
Tipo de estudo:
Relato de caso
/
Estudo experimental
/
Estudo observacional
/
Estudo prognóstico
Tópicos:
Vacinas
Limite:
Humanos
Idioma:
Inglês
/
Espanhol
Revista:
Med Clin (Barc)
Ano de publicação:
2022
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS