Discovery of novel non-peptidic and non-covalent small-molecule 3CL<sup>pro</sup> inhibitors as potential candidate for COVID-19 treatment.

Jiang, Zhidong; Feng, Bo; Zhang, Yumin; Nie, Tianqing; Liu, Hong; Li, Jia; Su, Haixia; Zhang, Leike; Zang, Yi; Zhou, Yu

Discovery of novel non-peptidic and non-covalent small-molecule 3CL^pro inhibitors as potential candidate for COVID-19 treatment.

Jiang, Zhidong; Feng, Bo; Zhang, Yumin; Nie, Tianqing; Liu, Hong; Li, Jia; Su, Haixia; Zhang, Leike; Zang, Yi; Zhou, Yu.

Jiang Z; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201203, China.
Feng B; Lingang Laboratory, Shanghai, 201203, China.
Zhang Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Nie T; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Liu H; Shenyang Pharmaceutical University, Shenyang, 110016, China.
Li J; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
Su H; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Zhang L; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Zang Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Zhou Y; Shenyang Pharmaceutical University, Shenyang, 110016, China.

Signal Transduct Target Ther ; 8(1): 209, 2023 05 22.

Artigo em Inglês | MEDLINE | ID: covidwho-2323873

Assuntos

COVID-19; Humanos; Tratamento Farmacológico da COVID-19; SARS-CoV-2; Sítios de Ligação

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: COVID-19 Limite: Humanos Idioma: Inglês Revista: Signal Transduct Target Ther Ano de publicação: 2023 Tipo de documento: Artigo País de afiliação: S41392-023-01482-9

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