Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.
Clin Chim Acta
; 505: 172-175, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: covidwho-5447
ABSTRACT
BACKGROUND:
There's an outbreak of a novel coronavirus (SARS-CoV-2) infection since December 2019, first in China, and currently with more than 80 thousand confirmed infection globally in 29 countries till March 2, 2020. Identification, isolation and caring for patients early are essential to limit human-to-human transmission including reducing secondary infections among close contacts and health care workers, preventing transmission amplification events. The RT-PCR detection of viral nucleic acid test (NAT) was one of the most quickly established laboratory diagnosis method in a novel viral pandemic, just as in this COVID-19 outbreak.METHODS:
4880 cases that had respiratory infection symptoms or close contact with COVID-19 patients in hospital in Wuhan, China, were tested for SARS-CoV-2 infection by use of quantitative RT-PCR (qRT-PCR) on samples from the respiratory tract. Positive rates were calculated in groups divided by genders or ages.RESULTS:
The positive rate was about 38% for the total 4880 specimens. Male and older population had a significant higher positive rates. However, 57% was positive among the specimens from the Fever Clinics. Binary logistic regression analysis showed that age, not gender, was the risk factor for SARS-CoV-2 infection in fever clinics.CONCLUSIONS:
Therefore, we concluded that viral NAT played an important role in identifying SARS-CoV-2 infection.Palavras-chave
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
/
DNA Viral
/
Infecções por Coronavirus
/
Reação em Cadeia da Polimerase em Tempo Real
/
Betacoronavirus
Tipo de estudo:
Estudo diagnóstico
/
Estudo experimental
/
Estudo observacional
/
Estudo prognóstico
/
Ensaios controlados aleatorizados
Limite:
Adolescente
/
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Meia-Idade
/
Jovem adulto
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Clin Chim Acta
Ano de publicação:
2020
Tipo de documento:
Artigo
País de afiliação:
J.cca.2020.03.009
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