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Coronavirus disease 2019 (COVID-19) in domestic animals and wildlife: advances and prospects in the development of animal models for vaccine and therapeutic research.
Sharun, Khan; Tiwari, Ruchi; Patel, Shailesh Kumar; Karthik, Kumaragurubaran; Iqbal Yatoo, Mohd; Malik, Yashpal S; Singh, Karam Pal; Panwar, Parmod Kumar; Harapan, Harapan; Singh, Raj Kumar; Dhama, Kuldeep.
  • Sharun K; Division of Surgery, ICAR-Indian Veterinary Research Institute , Bareilly, India.
  • Tiwari R; Department of Veterinary Microbiology and Immunology, College Of Veterinary Sciences, UP Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan (DUVASU) , Mathura, India.
  • Patel SK; Division of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly, India.
  • Karthik K; Central University Laboratory, Tamil Nadu Veterinary and Animal Sciences University , Chennai, India.
  • Iqbal Yatoo M; Division of Veterinary Clinical Complex, Faculty of Veterinary Sciences and Animal Husbandry, Shuhama, Alusteng Srinagar, Sher-E-Kashmir University of Agricultural Sciences and Technology of Kashmir , Srinagar, India.
  • Malik YS; Division of Biological Standardization, ICAR-Indian Veterinary Research Institute , Bareilly, India.
  • Singh KP; Division of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly, India.
  • Panwar PK; Department of Animal Husbandry, Directorate of Animal Husbandry , Lucknow, India.
  • Harapan H; Medical Research Unit, School of Medicine, Universitas Syiah Kuala , Banda Aceh, Indonesia.
  • Singh RK; Tropical Disease Centre, School of Medicine , Universitas Syiah Kuala, Banda Aceh, Indonesia.
  • Dhama K; Department of Microbiology, School of Medicine, Universitas Syiah Kuala , Banda Aceh, Indonesia.
Hum Vaccin Immunother ; 16(12): 3043-3054, 2020 12 01.
Artigo em Inglês | MEDLINE | ID: covidwho-759864
ABSTRACT
SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), is suspected to have been first contracted via animal-human interactions; it has further spread across the world by efficient human-to-human transmission. Recent reports of COVID-19 in companion animals (dogs and cats) and wild carnivores such as tigers have created a dilemma regarding its zoonotic transmission. Although in silico docking studies, sequence-based computational studies, and experimental studies have shown the possibility of SARS-CoV-2 infection and transmission in cats, ferrets, and other domestic/wild animals, the results are not conclusive of infection under natural conditions. Identifying the potential host range of SARS-CoV-2 will not only help prevent the possibility of human-to-animal and animal-to-human transmission but also assist in identifying efficient animal models that can mimic the clinical symptoms, transmission potential, and pathogenesis of the disease. Such an efficient animal model will accelerate the process of development and evaluation of vaccines, immunotherapeutics, and other remedies for SARS-CoV-2.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Zoonoses / Pesquisa Biomédica / Modelos Animais de Doenças / Vacinas contra COVID-19 / COVID-19 Tipo de estudo: Estudo experimental / Estudo prognóstico Tópicos: Vacinas Limite: Animais / Humanos Idioma: Inglês Revista: Hum Vaccin Immunother Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: 21645515.2020.1807802

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Zoonoses / Pesquisa Biomédica / Modelos Animais de Doenças / Vacinas contra COVID-19 / COVID-19 Tipo de estudo: Estudo experimental / Estudo prognóstico Tópicos: Vacinas Limite: Animais / Humanos Idioma: Inglês Revista: Hum Vaccin Immunother Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: 21645515.2020.1807802