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Exercise Intolerance in Long Covid After 24 Months From Severe Acute Disease: is There Room for Improvement? (preprint)
researchsquare; 2024.
Preprint
em Inglês
| PREPRINT-RESEARCHSQUARE | ID: ppzbmed-10.21203.rs.3.rs-4003335.v1
ABSTRACT
Introduction:
Long COVID is a complex and multisystemic condition, where dyspnea, fatigue, post-exertional malaise, cognitive impairment, decreased functional capacity, and deterioration in quality of life are the most incident clinical features. Few studies have reported cardiopulmonary alterations 24 months after severe COVID-19 infection.Objective:
to evaluate the functional capacity of individuals with persistent symptoms after severe COVID-19 infection compared to control individuals without symptomatic COVID or mild COVID after 24 months.Methods:
This is a case-control study assessing 34 individuals divided into 2 groups (severe COVID-19 with long COVID and a control group consisting of asymptomatic/mild acute COVID-19 with no long COVID) regarding functional capacity by 6-minute walk test (6MWT) associated with gas analysis, spirometry, respiratory muscle strength and quality of life.Results:
During the 6MWT, an important lower heart rate (HR) was observed for the COVID group, with greater exertional perception, a significant decrease in the distance covered, and a low value of O2 uptake (V̇O2) and minute ventilation, in addition to very low quality of life scores, especially in aspects of functional capacity and physical limitations.Conclusion:
individuals who have severe COVID-19 and persist with symptoms have low functional capacity, low V̇O2, low HR behavior, and low quality of life.
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Coleções:
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Base de dados:
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Assunto principal:
Doença Aguda
/
Transtornos Cognitivos
/
Dispneia
/
Fadiga
/
COVID-19
/
Síndrome Oculocerebrorrenal
Idioma:
Inglês
Ano de publicação:
2024
Tipo de documento:
Preprint
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