ABSTRACT
Calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic neoplasm, locally aggressive, characterized by sheets and nests of polyhedral epithelial cells exhibiting eosinophilic cytoplasm or less often clear cytoplasm. Additional features include nuclear pleomorphism without mitotic activity, concentric calcifications, and deposits of amyloid. Herein, we present an additional example of clear cell variant of CEOT occurring in a 25-year-old female. Microscopically, the tumor consisted on proliferation of epithelial cells with eosinophilic, clear vacuolated cytoplasm interspersed with focal areas of amyloid deposition. Tumor cells were immunopositive for AE1/AE3, CK14, CK19, ß-catenin, CD138, and p63. Key words:Calcifying epithelial odontogenic tumor, clear cell, histopathology, immunohistochemistry.
ABSTRACT
One hundred and fifty lepromatous patients of both sexes, with active lesions, were selected for this trough clinica, bacilloscopic and histopathological examinations. Two kinds of lesions were found: active and residual. Specific active were described as maculae, infiltrations, papules, nodules and plaques, with were most frequently found, in decreasing order, in uvula, solt and hard palate, and lips. Lesions presenting positive baciloscopy, even with an apparently normal mucosa, were always considered as active. Residual lesions were destrucution, atrophy and retraction of uvula, scars and nasopalatine perforation, more frequent in those patients with longer duration of the disease.
Subject(s)
Humans , Adult , Clinical Trials as Topic , Leprosy , Mouth Mucosa/pathology , Pathology, OralABSTRACT
One hunbred and fifty lepromatous patients of both sexes, with active lesions, were selected for this study through clinical, baclloscopic and histopathological examinations. Two kinds of lesions found: active and residual. Specific active lesions were described as maculas, inflitrations, papules, nodules and plaques, which were most frequently found, in decreasing order in uvula, soft and hard palate, and lips. Lesions presenting positive bacilloscopic, even with as apparenthy normal mucosa, were always considered as active. Residual lesions were destruction, atrophy and retraction of uvula, scars and nasopalatine perforation, more frequent in those patients with longer duration of the disease. According to bacilloscopy, oral lesions involute simultaneously with skin lesions. for this study, clinical, bacilloscopic and histopathological examinations were made, besides photographs of the most suggestive cases
